SCHEMBL7098404

SCHEMBL7098404

O=C(Nc1ccccc1)Nc1cccc(O)c1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TP53 P04637 2/20 0.68
SMN1; SMN2 Q16637 2/20 0.68
TSHR P16473 2/20 0.68
EPHX1 P07099 1/20 0.68
EPHX2 P34913 1/20 0.68
CDK9 P50750 1/20 0.68
CLK4 Q9HAZ1 1/20 0.68
MAOA P21397 1/20 0.68
MAOB P27338 1/20 0.68
BAZ1A Q9NRL2 1/20 0.68
KMT2A Q03164 8/20 0.67
MEN1 O00255 6/20 0.65
MAPT P10636 5/20 0.65
RAB9A P51151 3/20 0.65
LMNA P02545 2/20 0.65
NPC1 O15118 2/20 0.65
HTT P42858 2/20 0.65
HIF1A Q16665 1/20 0.64
MGLL Q99685 1/20 0.63
ALDH1A1 P00352 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9400341 0.94 ALDH1A1 (0.70) TP53SMN1; SMN2TSHREPHX1EPHX2
SCHEMBL22589002 0.88 SIRT1 (0.79) TP53MAOAMAOBBAZ1AKMT2A
SCHEMBL17193484 0.87 TP53 (0.81) TP53SMN1; SMN2TSHREPHX1EPHX2
SCHEMBL11431155 0.87 MAOA (0.56) TP53SMN1; SMN2TSHREPHX1EPHX2
SCHEMBL22589005 0.86 CA12 (0.60) MAOAMAOBBAZ1AKMT2AMEN1
SCHEMBL22588913 0.85 NPC1 (0.69) TP53SMN1; SMN2MAOAMAOBBAZ1A
SCHEMBL22588925 0.85 ALDH1A1 (0.83) TP53SMN1; SMN2TSHRMAOAMAOB
SCHEMBL31078919 0.85 BAZ1A (0.69) SMN1; SMN2MAOAMAOBBAZ1AKMT2A
SCHEMBL22588930 0.84 MAPT (0.75) MAOAMAOBBAZ1AKMT2AMEN1
SCHEMBL595025 0.83 ALDH1A1 (0.68) TP53SMN1; SMN2TSHRBAZ1AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3636446-B1 RECORDING MATERIAL, RECORDING SHEET AND USE OF A COMPOUND AS COLOUR-DEVELOPING AGENT NIPPON SODA CO (JP) 2025-04-16 EP disclosed
US-11529819-B2 Recording material and compound NIPPON SODA CO., LTD. (JP) 2022-12-20 US disclosed
EP-3535243-B1 SUBSTITUTED 9H-XANTHEN-9-ONE, 9H-THIOXANTHEN-9-ONE AND ACRIDIN-9(10H)-ONE DERIVATIVES AND RELATED COMPOUNDS CSF-1R INHIBITORS FOR THE TREATMENT OF CANCER AUCKLAND UNISERVICES LTD (NZ) 2021-12-15 EP disclosed
EP-3535243-B1 SUBSTITUTED 9H-XANTHEN-9-ONE, 9H-THIOXANTHEN-9-ONE AND ACRIDIN-9(10H)-ONE DERIVATIVES AND RELATED COMPOUNDS CSF-1R INHIBITORS FOR THE TREATMENT OF CANCER AUCKLAND UNISERVICES LTD (NZ) 2021-12-15 EP disclosed
CN-110709255-B Recording material and compound 日本曹达株式会社 2021-08-06 CN disclosed
US-11028064-B2 Tricyclic heterocyclic derivatives and uses thereof AUCKLAND UNISERVICES LIMITED (NZ) 2021-06-08 US disclosed
US-11028064-B2 Tricyclic heterocyclic derivatives and uses thereof AUCKLAND UNISERVICES LIMITED (NZ) 2021-06-08 US disclosed
WO-2020218003-A1 N,N'-DIARYLUREA DERIVATIVE AND THERMOSENSITIVE RECORDING MATERIAL USING SAME 三光株式会社 2020-10-29 WO disclosed
EP-3636446-A1 RECORDING MATERIAL AND COMPOUND Nippon Soda Co., Ltd. (JP) 2020-04-15 EP disclosed
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND NIPPON SODA CO., LTD. (JP) 2020-03-19 US disclosed
CN-110709255-A Recording material and compound 日本曹达株式会社 2020-01-17 CN disclosed
US-20190276423-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES AND USES THEREOF AUCKLAND UNISERVICES LIMITED (NZ) 2019-09-12 US disclosed
US-20190276423-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES AND USES THEREOF AUCKLAND UNISERVICES LIMITED (NZ) 2019-09-12 US disclosed
EP-3535243-A2 TRICYCLIC HETEROCYCLIC DERIVATIVES AND USES THEREOF Auckland Uniservices Limited (NZ) 2019-09-11 EP disclosed
CN-110139852-A Tricyclic heterocyclic derivatives and use thereof 奥克兰联合服务有限公司 2019-08-16 CN disclosed
CN-103709097-A 1,3-substituted carbamide or thiourea compound, preparation method thereof, pharmaceutical composition and application SHANGHAI INST MATERIA MEDICA 2014-04-09 CN disclosed
EP-0737896-B1 Photosensitive composition and photosensitive planographic printing plate KODAK POLYCHROME GRAPHICS JP (JP) 2003-08-27 EP disclosed
US-5731127-A WEAR RESISTANCE, SOLVENT RESISTANCE DAINIPPON INK AND CHEMICALS, INC. (JP) 1998-03-24 US disclosed
EP-0737896-A2 Photosensitive composition and photosensitive planographic printing plate DAINIPPON INK AND CHEMICALS, INC. (JP) 1996-10-16 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11028064-B2 Tricyclic heterocyclic derivatives and uses thereof CSF3R, CSF1R, FLT3 TP53 893/4885SMN1; SMN2 4412/4885TSHR 742/4885
US-11529819-B2 Recording material and compound H1-0, DOT1L, H1-4 TP53 2871/4885SMN1; SMN2 961/4885TSHR 4114/4885
US-20190276423-A1 TRICYCLIC HETEROCYCLIC DERIVATIVES AND USES THEREOF CSF3R, CSF1R, FLT3 TP53 893/4885SMN1; SMN2 4412/4885TSHR 742/4885
US-20200086669-A1 RECORDING MATERIAL AND COMPOUND H1-0, DOT1L, H1-4 TP53 2871/4885SMN1; SMN2 961/4885TSHR 4114/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.