Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | CRHBP | P24387 | 2/20 | 0.47 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 6/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2988744 | 0.76 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL5458081 | 0.73 | NPC1 (0.52) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL5455377 | 0.71 | ALDH1A1 (0.70) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL27815181 | 0.71 | MAPT (0.67) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL2153154 | 0.70 | MMP1 (0.75) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL31384411 | 0.69 | MEN1 (0.60) | ALDH1A1KDM4ELMNAHTTMEN1 | |
| SCHEMBL14861314 | 0.69 | MAPT (0.60) | ALDH1A1KDM4EMEN1KMT2AGAA | |
| SCHEMBL11059936 | 0.68 | GAA (0.72) | ALDH1A1HTTMEN1KMT2AGAA | |
| SCHEMBL11060793 | 0.68 | KDM4E (0.68) | ALDH1A1KDM4ELMNAMEN1KMT2A | |
| SCHEMBL223451 | 0.68 | MAPT (0.63) | ALDH1A1KDM4EMEN1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |