Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9728491 | 0.75 | NPC1 (0.53) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL5455380 | 0.73 | ALDH1A1 (0.51) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL3140037 | 0.71 | HPGD (0.64) | NPC1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL5458075 | 0.70 | ALDH1A1 (0.67) | KMT2AMEN1POLBALDH1A1KDM4E | |
| SCHEMBL3397939 | 0.69 | NPC1 (0.60) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL2153795 | 0.69 | HTT (0.71) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL19294522 | 0.68 | KDM4E (0.74) | NPC1KMT2AMEN1ALDH1A1KDM4E | |
| SCHEMBL29231950 | 0.68 | HPGD (0.66) | NPC1KMT2APOLBALDH1A1KDM4E | |
| SCHEMBL6469132 | 0.67 | MEN1 (0.71) | NPC1KMT2AMEN1POLBALDH1A1 | |
| SCHEMBL1694938 | 0.66 | LMNA (0.41) | NPC1KMT2AMEN1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |