Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TAS2R14 | Q9NYV8 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5446944 | 0.91 | APOBEC3A (0.41) | ALDH1A1HPGDMAPTTAS2R14MEN1 | |
| SCHEMBL5446129 | 0.89 | TAS2R14 (0.40) | HPGDMAPTTHRBATG4BTAS2R14 | |
| SCHEMBL14612641 | 0.86 | ACHE (0.45) | ALDH1A1HPGDMAPTTHRBATG4B | |
| SCHEMBL5451571 | 0.80 | ALDH1A1 (0.37) | ALDH1A1TAS2R14EPHX2NR1H4TSHR | |
| SCHEMBL14612688 | 0.76 | HDAC6 (0.37) | ALDH1A1MAPTEPHX2NR1H4 | |
| SCHEMBL17187158 | 0.71 | HPGD (0.41) | ALDH1A1HPGDMAPTTDP1MEN1 | |
| Benzoic Acid SCHEMBL28244536 | 0.66 | TSHR (0.67) | ALDH1A1TDP1TSHRSRD5A2 | |
| Triphenylene SCHEMBL28540371 | 0.65 | TSHR (0.72) | ALDH1A1SMN1; SMN2TSHRSRD5A2 | |
| SCHEMBL51938 | 0.65 | TDP1 (0.55) | ALDH1A1MAPTTHRBTDP1MEN1 | |
| SCHEMBL29240 | 0.65 | ACHE (0.59) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070031854-A1 | Novel 10,10'-substituted-9,9'-biacridilidine luminescent molecules their preparation and uses | KATSILOMETES GEORGE W | 2007-02-08 | — | — | US | disclosed |
| US-20020034828-A1 | NOVEL 10,10'-SUBSTITUTED-9,9'-BIACRIDINE LUMINESCENT MOLECULES AND THEIR PREPARATION | PIERCE CHEMICAL COMPANY | 2002-03-21 | — | — | US | disclosed |
| EP-1026156-A2 | Novel 10, 10'-substituted-9,9'-biacridine luminescent molecules and their preparation | PIERCE CHEMICAL COMPANY (US) | 2000-08-09 | — | — | EP | disclosed |