Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.65 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.54 |
| ▸ | CYTH3 | O43739 | 1/20 | 0.54 |
| ▸ | AKT1 | P31749 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5453548 | 0.85 | MAPT (0.67) | MAPTRAB9AALDH1A1HPGDMEN1 | |
| SCHEMBL5445610 | 0.81 | MAPT (0.71) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL30542211 | 0.80 | ALDH1A1 (0.60) | MAPTNPC1ALDH1A1HPGDMEN1 | |
| SCHEMBL14096534 | 0.76 | RAB9A (0.62) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL14096350 | 0.76 | SIRT2 (0.56) | MAPTRAB9ANPC1ALDH1A1MEN1 | |
| SCHEMBL5448364 | 0.76 | ALDH1A1 (0.66) | MAPTRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL5448244 | 0.76 | MAPT (0.86) | MAPTRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL5450571 | 0.75 | MAPT (0.76) | MAPTRAB9ANPC1ALDH1A1HPGD | |
| SCHEMBL13454585 | 0.75 | GPR55 (0.67) | MAPTRAB9ANPC1POLBALDH1A1 | |
| SCHEMBL12838838 | 0.73 | ALDH1A1 (0.61) | MAPTRAB9ANPC1POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101129295-B | There is the binary initiator system of good storage stability and especially suitable for acidic system | HERAEUS KULZER GMBH (DE) | 2016-02-10 | — | — | CN | disclosed |
| US-20070040151-A1 | Two-component initiator system (amine-free) with very good storage stability and particular suitability for acid systems | HERAEUS KULZER GMBH (DE) | 2007-02-22 | — | — | US | disclosed |