Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MELK | Q14680 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 1/20 | 0.57 |
| ▸ | CASP3 | P42574 | 1/20 | 0.57 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.57 |
| ▸ | CLK2 | P49760 | 1/20 | 0.52 |
| ▸ | CLK3 | P49761 | 1/20 | 0.52 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.52 |
| ▸ | F2 | P00734 | 1/20 | 0.51 |
| ▸ | PLG | P00747 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | PLAT | P00750 | 1/20 | 0.51 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.51 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 3/20 | 0.48 |
| ▸ | ITGA2B | P08514 | 3/20 | 0.48 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL1188301 | 0.91 | MELK (0.53) | MELKNPC1RAB9APOLBCASP3 | |
| Hydrochloric Acid SCHEMBL1188011 | 0.90 | NPC1 (0.68) | MELKNPC1RAB9APOLBCASP3 | |
| Hydrochloric Acid SCHEMBL1187336 | 0.89 | NPC1 (0.70) | MELKNPC1RAB9APOLBCASP3 | |
| SCHEMBL5467483 | 0.83 | RAB9A (0.73) | NPC1RAB9APOLBCASP3SENP7 | |
| Hydrochloric Acid SCHEMBL1188841 | 0.82 | RAB9A (0.71) | NPC1RAB9APOLBCASP3SENP7 | |
| Hydrochloric Acid SCHEMBL1188479 | 0.82 | MEN1 (0.56) | MELKNPC1RAB9APOLBCASP3 | |
| SCHEMBL3003689 | 0.81 | F2 (0.54) | MELKCLK2CLK3DYRK1AF2 | |
| Hydrochloric Acid SCHEMBL1187815 | 0.81 | ROCK2 (0.49) | MELKNPC1RAB9APOLBCASP3 | |
| Hydrochloric Acid SCHEMBL1188393 | 0.81 | NPC1 (0.66) | MELKNPC1RAB9APOLBCASP3 | |
| SCHEMBL5458163 | 0.80 | POLB (0.58) | MELKNPC1RAB9APOLBCASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | MELK 3866/4885NPC1 1089/4885RAB9A 1528/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.