Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.47 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452783 | 0.80 | NUDT1 (0.51) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL5452827 | 0.76 | NUDT1 (0.47) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL27681040 | 0.73 | ALDH1A1 (0.76) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL4262573 | 0.73 | HTT (0.51) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL3094649 | 0.72 | KDM4E (0.63) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL26337500 | 0.71 | ALDH1A1 (0.59) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL5445110 | 0.71 | NUDT1 (0.51) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL17501810 | 0.71 | KDM4E (0.71) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL1013949 | 0.71 | POLB (0.59) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA | |
| SCHEMBL15733255 | 0.70 | KDM4E (0.47) | ALDH1A1KDM4EL3MBTL1MAPK1PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | ALDH1A1 309/4885KDM4E 521/4885L3MBTL1 4215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.