Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.42 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.41 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5452783 | 0.95 | NUDT1 (0.51) | NUDT1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5450737 | 0.82 | ALDH1A1 (0.47) | NUDT1KDM4EHSD17B10TSHRALDH1A1 | |
| SCHEMBL5445110 | 0.82 | NUDT1 (0.51) | NUDT1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5450960 | 0.80 | HRH4 (0.42) | KDM4EALDH1A1HTTPOLBSMN1; SMN2 | |
| SCHEMBL5453324 | 0.79 | KDM4E (0.52) | NUDT1KDM4EHSD17B10TSHRALDH1A1 | |
| SCHEMBL5462475 | 0.78 | KDM4E (0.40) | KDM4EHSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL5457164 | 0.77 | NUDT1 (0.46) | NUDT1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL5455711 | 0.76 | ALDH1A1 (0.48) | KDM4EMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL5444088 | 0.73 | CRHR1 (0.37) | MEN1KMT2ATSHRALDH1A1POLB | |
| SCHEMBL5455961 | 0.73 | P2RY12 (0.37) | KDM4EHSD17B10MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ASTRAZENECA AB (SE) | 2007-11-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070259849-A1 | Azine-Carboxamides as Anti-Cancer Agents | ARAF, BRAF, RAF1 | NUDT1 779/4885KDM4E 521/4885HSD17B10 4741/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.