Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SOAT1 | P35610 | 8/20 | 0.37 |
| ▸ | SOAT2 | O75908 | 5/20 | 0.37 |
| ▸ | PRKCD | Q05655 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9136876 | 0.87 | ALDH1A1 (0.41) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL4661522 | 0.86 | — | — | |
| SCHEMBL16500668 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1MAPTSOAT1SOAT2 | |
| SCHEMBL6466586 | 0.75 | KDM4E (0.47) | KDM4EALDH1A1MAPTSOAT1SOAT2 | |
| SCHEMBL9402165 | 0.71 | LMNA (0.33) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL5450009 | 0.71 | KDM4E (0.40) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL19174975 | 0.70 | CCR2 (0.40) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL20031168 | 0.70 | NPC1 (0.41) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL21755171 | 0.70 | SRD5A1 (0.36) | KDM4EMEN1ALDH1A1MAPTPKM | |
| SCHEMBL17867144 | 0.70 | KDM4E (0.43) | KDM4EALDH1A1MAPTSOAT1PRKCD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | BASF AKTIENGESELLSCHAFT (DE) | 2007-06-07 | — | — | US | disclosed |
| EP-1682473-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF Aktiengesellschaft (DE) | 2006-07-26 | — | — | EP | disclosed |
| WO-2005042454-A1 | METHOD FOR THE PRODUCTION OF 2,2'-DIHYDROXYBIPHENYLS | BASF AKTIENGESELLSCHAFT (DE) | 2005-05-12 | — | — | WO | disclosed |
| US-4058462-A | System for sustained release of phenolic material from porous granules of insoluble polymeric phenolic complexes | GAF CORPORATION (US) | 1977-11-15 | — | — | US | disclosed |
| US-3985540-A | Metal complexes of hydroxyquinoline and polymeric porous granules | GAF CORPORATION (US) | 1976-10-12 | — | — | US | disclosed |
| US-3970606-A | N-vinyl lactam interpolymers useful as thickening agents | GAF CORPORATION (US) | 1976-07-20 | — | — | US | disclosed |
| US-3954682-A | GRANULES OR BEADS | GAF CORPORATION (US) | 1976-05-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129578-A1 | Method for the production of 2,2'-dihydroxybiphenyls | HAO2, DAO, DDO | KDM4E 2614/4885MEN1 4248/4885ALDH1A1 1084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.