Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 2/20 | 0.37 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20901331 | 0.81 | METAP1 (0.44) | METAP1NAMPTATRALDH1A1L3MBTL1 | |
| SCHEMBL1940995 | 0.74 | GSK3B (0.40) | ATRCYP17A1MAPK1MAP4K4 | |
| SCHEMBL27967000 | 0.74 | RAB9A (0.49) | METAP1NAMPTATRL3MBTL1RAB9A | |
| SCHEMBL15266282 | 0.74 | METAP1 (0.56) | METAP1NAMPTATRRAB9ACYP17A1 | |
| SCHEMBL68279 | 0.74 | RAB9A (0.54) | METAP1ALDH1A1L3MBTL1RAB9AMAPK1 | |
| SCHEMBL29919656 | 0.74 | RAB9A (0.54) | METAP1ALDH1A1L3MBTL1RAB9AMAPK1 | |
| SCHEMBL32665001 | 0.73 | NPC1 (0.42) | METAP1NAMPTATRALDH1A1L3MBTL1 | |
| SCHEMBL30850156 | 0.73 | METAP1 (0.39) | METAP1NAMPTATRALDH1A1L3MBTL1 | |
| SCHEMBL27289163 | 0.73 | NPC1 (0.42) | METAP1NAMPTATRALDH1A1L3MBTL1 | |
| SCHEMBL30850160 | 0.73 | METAP1 (0.39) | METAP1NAMPTATRALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | METAP1 434/4885NAMPT 324/4885ATR 4786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.