Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 6/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5455878 | 0.84 | MAPT (0.55) | MAPT | |
| SCHEMBL221664 | 0.82 | KMT2A (0.48) | MAPT | |
| SCHEMBL5469275 | 0.81 | MAPT (0.43) | MAPTCYP3A4 | |
| SCHEMBL10352194 | 0.81 | MAPT (0.56) | ARMAPTCYP3A4 | |
| SCHEMBL13481164 | 0.81 | MAPT (0.63) | ARMAPTPGRCYP3A4 | |
| SCHEMBL5467390 | 0.81 | MAPT (0.44) | MAPTCYP3A4 | |
| SCHEMBL5473053 | 0.79 | ALDH1A1 (0.36) | AR | |
| SCHEMBL5460796 | 0.78 | AR (0.47) | ARMAPTPGRCYP3A4 | |
| SCHEMBL2746435 | 0.78 | AR (0.50) | ARMAPTPGRCYP3A4 | |
| SCHEMBL10352011 | 0.78 | MAPT (0.52) | ARMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | AR 3268/4885MAPT 758/4885PGR 2599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.