Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | NCF1 | P14598 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | PDE2A | O00408 | 1/20 | 0.46 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.46 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5456024 | 0.86 | ALDH1A1 (0.57) | CYP1A2CYP3A4CYP2C19NCF1ALDH1A1 | |
| SCHEMBL13035828 | 0.81 | ALDH1A1 (0.56) | ALDH1A1HTTPOLBPDE2APDE3B | |
| SCHEMBL13541756 | 0.81 | CXCL8 (0.40) | NCF1ALDH1A1PDE2APDE3BPDE3A | |
| SCHEMBL17582786 | 0.80 | NCF1 (0.46) | CYP1A2CYP3A4CYP2C19NCF1ALDH1A1 | |
| SCHEMBL14112985 | 0.79 | PDE3B (0.46) | NCF1ALDH1A1HTTPOLBPDE2A | |
| SCHEMBL13604063 | 0.79 | SMN1; SMN2 (0.50) | NCF1ALDH1A1HTTPDE2APDE3B | |
| SCHEMBL18965901 | 0.78 | KDM4E (0.43) | ALDH1A1HTTPOLBHPGDMEN1 | |
| SCHEMBL13541754 | 0.77 | ACSS2 (0.49) | ALDH1A1PDE2APDE3BPDE3ACA2 | |
| SCHEMBL4650051 | 0.77 | MTNR1A (0.56) | ALDH1A1HTTPOLBPDE2APDE3B | |
| SCHEMBL979518 | 0.77 | TLR8 (0.58) | ALDH1A1HTTPDE2APDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023274251-A1 | POLYCYCLIC COMPOUND FOR INHIBITING RNA HELICASE DHX33, AND APPLICATION OF COMPOUND | 深圳开悦生命科技有限公司 | 2023-01-05 | — | — | WO | disclosed |
| US-20070232673-A1 | 2-Imino-benzimidazoles | ABBOTT LABORATORIES | 2007-10-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070232673-A1 | 2-Imino-benzimidazoles | CYP2C19, UGT2B7, UGT2B17 | CYP1A2 9/4885CYP3A4 7/4885CYP2C19 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.