Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 8/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADH1C | P00326 | 1/20 | 0.38 |
| ▸ | ADH1A | P07327 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.35 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | XBP1 | P17861 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449617 | 1.00 | SLC6A4 (0.40) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C | |
| SCHEMBL10778320 | 0.89 | ADH1A (0.45) | ADH1CADH1AS1PR1S1PR3TSHR | |
| SCHEMBL3891941 | 0.79 | OPRM1 (0.43) | ADH1CADH1AOPRD1OPRM1S1PR1 | |
| SCHEMBL5456713 | 0.77 | SLC6A4 (0.39) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C | |
| SCHEMBL2281424 | 0.77 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2ADH1C | |
| SCHEMBL5195333 | 0.76 | MAPT (0.39) | ADH1CADH1ANPSR1L3MBTL1 | |
| SCHEMBL5197653 | 0.76 | MAPT (0.39) | ADH1CADH1ANPSR1L3MBTL1 | |
| SCHEMBL13622839 | 0.75 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL27624686 | 0.74 | SLC6A4 (0.42) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 | |
| SCHEMBL16795227 | 0.74 | SLC6A4 (0.44) | SLC6A4SLC6A2SLC6A3KCNH2EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI-AVENTIS (FR) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070191364-A1 | AMINOPIPERIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | MC4R, MC5R, TAAR5 | SLC6A4 728/4885SLC6A2 276/4885SLC6A3 478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.