Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 5/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.54 |
| ▸ | FDPS | P14324 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.43 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.41 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.41 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10271979 | 0.80 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL5021664 | 0.80 | FDPS (0.57) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL2646363 | 0.80 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL5021553 | 0.80 | FDPS (0.57) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL8625514 | 0.79 | CYP11B1 (0.50) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| Bromide SCHEMBL2503415 | 0.78 | CYP11B1 (0.53) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL21692173 | 0.78 | ATM (0.62) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL722248 | 0.78 | ATM (0.62) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL16135139 | 0.77 | CYP11B1 (0.51) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL17102863 | 0.76 | GRIN2D (0.47) | CYP11B1CYP11B2GRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | claimed |
| EP-1638925-A1 | PROTEASE INHIBITORS | Prozymex A/S (DK) | 2006-03-29 | — | — | EP | claimed |
| WO-2004110988-A1 | PROTEASE INHIBITORS | PROZYMEX A/S (DK) | 2004-12-23 | — | — | WO | claimed |
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | disclosed |
| EP-1638925-A1 | PROTEASE INHIBITORS | Prozymex A/S (DK) | 2006-03-29 | — | — | EP | disclosed |
| WO-2004110988-A1 | PROTEASE INHIBITORS | PROZYMEX A/S (DK) | 2004-12-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | CTSC, DPP7, BACE1 | CYP11B1 1965/4885CYP11B2 1431/4885FDPS 2947/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.