Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 4/20 | 0.50 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.50 |
| ▸ | FDPS | P14324 | 3/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 2/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.40 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.38 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5498487 | 0.84 | DRD2 (0.50) | CYP11B1CYP11B2DRD2DRD4DRD3 | |
| SCHEMBL8625517 | 0.82 | PRMT6 (0.57) | CYP11B1CYP11B2FDPSATMEPHX2 | |
| SCHEMBL29373657 | 0.82 | FDPS (0.53) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL402768 | 0.82 | FDPS (0.53) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL5456894 | 0.79 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL27649705 | 0.78 | ADH1B (0.55) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL7386284 | 0.77 | CYP11B1 (0.46) | CYP11B1CYP11B2FDPSATMMKNK1 | |
| SCHEMBL2646363 | 0.76 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL5021664 | 0.76 | FDPS (0.57) | CYP11B1CYP11B2FDPSDRD2DRD4 | |
| SCHEMBL10271979 | 0.76 | CYP11B1 (0.54) | CYP11B1CYP11B2FDPSDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5767132-A | CENTRAL NERVOUS SYSTEM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-06-16 | — | — | US | disclosed |