Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.78 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.78 |
| ▸ | MEN1 | O00255 | 3/20 | 0.75 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.75 |
| ▸ | TSHR | P16473 | 3/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.75 |
| ▸ | GFER | P55789 | 1/20 | 0.71 |
| ▸ | GAA | P10253 | 2/20 | 0.70 |
| ▸ | MAPT | P10636 | 2/20 | 0.68 |
| ▸ | HPGD | P15428 | 1/20 | 0.68 |
| ▸ | POLB | P06746 | 1/20 | 0.67 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | USP2 | O75604 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.54 |
| ▸ | GSK3A | P49840 | 1/20 | 0.53 |
| ▸ | GSK3B | P49841 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16671708 | 0.86 | ALDH1A1 (1.00) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL5468600 | 0.78 | GSK3A (0.66) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL14492360 | 0.77 | GSK3A (0.73) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL5455140 | 0.76 | HDAC1 (0.70) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL5457428 | 0.76 | MEN1 (0.65) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL12177294 | 0.75 | ALDH1A1 (0.69) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL9327964 | 0.74 | KMT2A (0.68) | ALDH1A1MEN1KMT2ASMN1; SMN2HPGD | |
| SCHEMBL5465566 | 0.74 | GAA (0.60) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL9825516 | 0.73 | HTT (0.61) | ALDH1A1HSD17B10MEN1KMT2ATSHR | |
| SCHEMBL1421312 | 0.73 | GSK3A (0.67) | ALDH1A1HSD17B10MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | ALDH1A1 1861/4885HSD17B10 2022/4885MEN1 2892/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.