Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.61 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9825395 | 0.84 | DRD2 (0.48) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL9826999 | 0.80 | MAPT (0.53) | HTTTSHRALDH1A1LMNAKDM4E | |
| SCHEMBL11391291 | 0.76 | HTT (1.00) | HTTTP53MEN1KMT2ATSHR | |
| SCHEMBL5457230 | 0.73 | ALDH1A1 (0.78) | HTTMEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL9825290 | 0.73 | KMT2A (0.43) | MEN1KMT2ATSHRLMNA | |
| SCHEMBL6796523 | 0.71 | NPC1 (0.70) | HTTTP53MEN1KMT2AALDH1A1 | |
| SCHEMBL6893687 | 0.71 | ALDH1A1 (0.79) | TP53MEN1KMT2AALDH1A1NPC1 | |
| SCHEMBL9826578 | 0.70 | ALDH1A1 (0.60) | HTTTSHRALDH1A1HSD17B10KDM4E | |
| SCHEMBL12177294 | 0.69 | ALDH1A1 (0.69) | HTTTP53MEN1KMT2ATSHR | |
| SCHEMBL11147683 | 0.68 | ALDH1A1 (0.90) | HTTTP53MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0203743-B1 | OXOTHIAZOLIDINE COMPOUND | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1991-02-06 | — | — | EP | disclosed |
| US-4764514-A | COGNITIONACTIVATORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1988-08-16 | — | — | US | disclosed |
| EP-0203743-A1 | Oxothiazolidine compound | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-12-03 | — | — | EP | disclosed |