Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSK | P43235 | 4/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | BACE1 | P56817 | 8/20 | 0.50 |
| ▸ | CTSS | P25774 | 4/20 | 0.50 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.49 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA7 | P43166 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5457812 | 1.00 | CTSK (0.55) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL17097354 | 0.90 | ATM (0.58) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL16482788 | 0.90 | ATM (0.58) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL16463143 | 0.90 | ATM (0.58) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL17106947 | 0.89 | CTSK (0.65) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL16462512 | 0.89 | CTSK (0.65) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL10571494 | 0.88 | BACE1 (0.60) | BACE1REN | |
| SCHEMBL7429906 | 0.87 | CTSK (0.49) | CTSKATMBACE1CTSSCTSL | |
| SCHEMBL21457973 | 0.83 | CTSS (0.56) | CTSKATMCTSSCTSLCTSB | |
| SCHEMBL21457987 | 0.83 | CTSS (0.56) | CTSKATMCTSSCTSLCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276019-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | AXYS PHARMACEUTICALS, INC. (US) | 2007-11-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276019-A1 | Haloalkyl Containing Compounds as Cysteine Protease Inhibitors | CTSF, CTSS, CTSE | CTSK 7/4885ATM 4083/4885BACE1 494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.