Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4924785 | 0.87 | ALDH1A1 (0.49) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL10651810 | 0.84 | CYP1A2 (0.45) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL27669113 | 0.82 | MEN1 (0.46) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL5456877 | 0.79 | NPC1 (0.42) | CYP1A2MAPK1CYP2C19SMN1; SMN2KMT2A | |
| SCHEMBL13044544 | 0.79 | KMT2A (0.44) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL6076413 | 0.77 | SMN1; SMN2 (0.64) | CYP1A2CYP3A4SMN1; SMN2MEN1KMT2A | |
| SCHEMBL20865742 | 0.76 | CASP1 (0.46) | MAPTMAPK1CYP2C19SMN1; SMN2MEN1 | |
| SCHEMBL896383 | 0.74 | ALDH1A1 (0.50) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL2305312 | 0.74 | TSHR (0.48) | CYP1A2CYP3A4CYP2D6MAPTMAPK1 | |
| SCHEMBL896714 | 0.74 | ALDH1A1 (0.47) | CYP1A2CYP3A4MAPK1CYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | CYP1A2 2570/4885CYP3A4 3044/4885CYP2D6 1049/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.