Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.35 |
| ▸ | NEK2 | P51955 | 1/20 | 0.35 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29713864 | 0.79 | ALDH1A1 (0.44) | MAPTGAAKDM4ECA2ALDH1A1 | |
| SCHEMBL545805 | 0.79 | ALDH1A1 (0.44) | MAPTGAAKDM4ECA2ALDH1A1 | |
| SCHEMBL20836423 | 0.78 | MAPT (0.44) | MAPTGAAKDM4EMCL1CA2 | |
| SCHEMBL31483713 | 0.78 | MAPT (0.44) | MAPTGAAKDM4EMCL1CA2 | |
| SCHEMBL6675092 | 0.77 | ALDH1A1 (0.31) | GAAALDH1A1 | |
| Hydrochloric Acid SCHEMBL2872399 | 0.77 | MAPT (0.43) | MAPTGAAKDM4ECA2ALDH1A1 | |
| SCHEMBL10340767 | 0.77 | MAPT (0.43) | MAPTGAAKDM4ECA2ALDH1A1 | |
| SCHEMBL7944113 | 0.76 | CHEK1 (0.47) | MAPTGAAKDM4EMCL1CA2 | |
| SCHEMBL29643330 | 0.76 | CA2 (0.53) | MAPTGAAKDM4EMCL1CA2 | |
| SCHEMBL2960296 | 0.76 | CA2 (0.53) | MAPTGAAKDM4EMCL1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558857-A1 | Method for the manufacture of P-bromodimethyl aniline | IMI (TAMI) INSTITUTE FOR RESEARCH & DEVELOPMENT LTD. (IL) | 1993-09-08 | — | — | EP | disclosed |