Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.45 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 11/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.35 |
| ▸ | AXL | P30530 | 1/20 | 0.35 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.35 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.35 |
| ▸ | DHFR | P00374 | 2/20 | 0.34 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8348566 | 0.81 | ERN1 (0.50) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL17127157 | 0.81 | ATM (0.48) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL22089054 | 0.79 | ATM (0.67) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL5465791 | 0.78 | KIF11 (0.52) | MKNK1 | |
| SCHEMBL4814582 | 0.78 | ATM (0.45) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL1005178 | 0.77 | MAOA (0.44) | KCNH2 | |
| SCHEMBL22428553 | 0.77 | ATM (0.64) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL22428530 | 0.77 | ATM (0.64) | ATMCYP2A6ERN1CNR1CNR2 | |
| SCHEMBL4583478 | 0.75 | ATM (0.50) | ATMCYP2A6ERN1 | |
| SCHEMBL5656090 | 0.75 | CNR1 (0.43) | ATMCYP2A6ERN1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | claimed |
| US-20070099958-A1 | Protease inhibitors | PROZYMEX A/S (DK) | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099958-A1 | Protease inhibitors | CTSC, DPP7, BACE1 | ATM 2956/4885CYP2A6 906/4885ERN1 3785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.