Sugi Predict

Sugi Predict / Compounds / SCHEMBL1005178

SCHEMBL1005178

SCHEMBL1005178

C[CH]c1cccc(-c2ccccc2)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MAOA P21397 1/20 0.44
▸ TRIM24 O15164 1/20 0.44
▸ TRIM33 Q9UPN9 1/20 0.44
▸ ALDH1A1 P00352 1/20 0.43
▸ PTGS2 P35354 1/20 0.41
▸ MGLL Q99685 2/20 0.40
▸ CA12 O43570 1/20 0.39
▸ CA1 P00915 1/20 0.39
▸ CA2 P00918 1/20 0.39
▸ CA9 Q16790 1/20 0.39
▸ KMO O15229 1/20 0.39
▸ HDAC4 P56524 1/20 0.39
▸ HDAC2 Q92769 1/20 0.39
▸ HDAC8 Q9BY41 1/20 0.39
▸ BCL2L1 Q07817 1/20 0.38
▸ BAD Q92934 1/20 0.38
▸ ALOX5 P09917 1/20 0.38
▸ KCNH2 Q12809 1/20 0.38
▸ TP53 P04637 1/20 0.38
▸ PRSS1 P07477 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5465791 0.83 KIF11 (0.52) —
SCHEMBL31558750 0.82 PLAAT3 (0.44) MAOATRIM24TRIM33ALDH1A1PTGS2
SCHEMBL27946719 0.82 PLAAT3 (0.44) MAOATRIM24TRIM33ALDH1A1PTGS2
SCHEMBL27567318 0.82 PLAAT3 (0.44) MAOATRIM24TRIM33ALDH1A1PTGS2
SCHEMBL2843934 0.80 MAOA (0.48) MAOATRIM24TRIM33ALDH1A1PTGS2
SCHEMBL6643752 0.80 CYP1A1 (0.42) TRIM24TRIM33ALDH1A1PTGS2CA12
SCHEMBL2186055 0.79 TP53 (0.40) MAOAALDH1A1TP53
SCHEMBL530889 0.78 NFE2L2 (0.58) MAOAHDAC2HDAC8BCL2L1BAD
SCHEMBL7535716 0.78 NFE2L2 (0.58) MAOAHDAC2HDAC8BCL2L1BAD
SCHEMBL8644523 0.77 TRIM24 (0.46) MAOATRIM24TRIM33ALDH1A1PTGS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11629129-B2 Microbiocidal picolinamide derivatives SYNGENTA PARTICIPATIONS AG (CH) 2023-04-18 — — US disclosed
CN-112674083-B Dispersible oil suspending agent of bifenthrin and fluopicolide and preparation method and application thereof 山东潍坊润丰化工股份有限公司 2022-11-01 — — CN disclosed
CN-112931526-A Water dispersible granule containing bifenthrin and fluopicolide as well as preparation method and application thereof 山东潍坊润丰化工股份有限公司 2021-06-11 — — CN disclosed
US-20210114984-A1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES SYNGENTA PARTICIPATIONS AG (CH) 2021-04-22 — — US disclosed
CN-112674083-A Dispersible oil suspending agent of bifenthrin and fluopicolide and preparation method and application thereof 山东潍坊润丰化工股份有限公司 2021-04-20 — — CN disclosed
CN-111418603-A Water suspending agent containing bifenthrin and fluopyram, and preparation method and application thereof 山东潍坊润丰化工股份有限公司 2020-07-17 — — CN disclosed
CN-110199989-A A kind of composition pesticide and its preparation method and application containing Biphenthrin and fluorobenzene pyrrole bacterium amine 青岛润农化工有限公司 2019-09-06 — — CN disclosed
US-10289002-B2 Electron beam resist underlayer film-forming composition containing lactone-structure-containing polymer NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2019-05-14 — — US disclosed
US-10042247-B2 Mask blank, method for manufacturing mask blank and transfer mask HOYA CORPORATION (JP) 2018-08-07 — — US disclosed
US-20170285460-A1 MASK BLANK, METHOD FOR MANUFACTURING MASK BLANK AND TRANSFER MASK HOYA CORPORATION (JP) 2017-10-05 — — US disclosed
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance CHISSO CORPORATION (JP) 2006-03-09 — — US disclosed
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers JNC CORPORATION (JP) 2005-12-29 — — US disclosed
US-20050250925-A1 Silicon compound JNC CORPORATION (JP) 2005-11-10 — — US disclosed
US-20050215807-A1 Silsesquioxane derivative JNC CORPORATION (JP) 2005-09-29 — — US disclosed
EP-1550664-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-07-06 — — EP disclosed
EP-1548020-A1 SILICON COMPOUND CHISSO CORPORATION (JP) 2005-06-29 — — EP disclosed
US-20050033077-A1 Production process for silicon compound and the same JNC CORPORATION (JP) 2005-02-10 — — US disclosed
US-20040068074-A1 Production process for silsesquioxane derivative having functional group and silsesquioxane derivative JNC CORPORATION (JP) 2004-04-08 — — US disclosed
US-20040030084-A1 Production process for silsesquioxane derivative and silsesquioxane derivative JNC CORPORATION (JP) 2004-02-12 — — US disclosed
US-6248918-B1 BIS(DIHYDROCARBYLPHOSPHINOYLALKYL)-1,1'-BINAPHTHOL) AND RARE EARTH OR GROUP 3A METAL SALTS NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2001-06-19 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060052623-A1 Having two cyclotetrasiloxne rings connected by O-Si groups obtained through hydrolysis and condensation of trifunctional hydrolyzable silicon compounds; functionalization; fireproofing, thermostability, weathproofing, photostability, dielectric, hardness, strength and chemical resistance STS, PFAS, POLQ MAOA 1362/4885TRIM24 4408/4885TRIM33 4045/4885
US-20050215807-A1 Silsesquioxane derivative STS, SFXN1, SULT1A1 MAOA 3213/4885TRIM24 3245/4885TRIM33 3670/4885
US-20210114984-A1 MICROBIOCIDAL PICOLINAMIDE DERIVATIVES PRF1, CASP1, MSR1 MAOA 647/4885TRIM24 4320/4885TRIM33 4429/4885
US-20050288468-A1 Cyclic polysilsequisiloxanes substituted with a group containing a sulfonyl halide, especially ahalosulfonylphenyl group; living radical polymerization initiators, particularly for preparing acrylic polymers STS, SULT1A1, SRM MAOA 4138/4885TRIM24 2147/4885TRIM33 3086/4885
US-11629129-B2 Microbiocidal picolinamide derivatives PRF1, CASP1, MSR1 MAOA 647/4885TRIM24 4320/4885TRIM33 4429/4885
US-20050033077-A1 Production process for silicon compound and the same STS, SMS, SFXN1 MAOA 2223/4885TRIM24 2686/4885TRIM33 3496/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.