Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.54 |
| ▸ | PPARA | Q07869 | 2/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | CACNA2D1 | P54289 | 3/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | CNR1 | P21554 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 1/20 | 0.46 |
| ▸ | PTGIR | P43119 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7053659 | 0.88 | SLC6A4 (0.68) | SLC6A4CACNA2D1SLC6A2CNR1KDM4E | |
| Decanoic Acid SCHEMBL144254 | 0.88 | PPARA (0.51) | PPARAPPARGCNR1CNR2PTGIR | |
| Fluoxetine SCHEMBL7905216 | 0.80 | SLC6A4 (0.72) | SLC6A4SLC6A2CNR1KDM4EMEN1 | |
| Fluoxetine SCHEMBL27614388 | 0.80 | SLC6A4 (0.72) | SLC6A4SLC6A2CNR1KDM4EMEN1 | |
| SCHEMBL5458415 | 0.78 | PPARA (0.45) | PPARAPPARGCNR1CNR2PTGIR | |
| SCHEMBL144255 | 0.76 | PPARA (0.47) | PPARAPPARGCNR1CNR2PTGIR | |
| Fluoxetine SCHEMBL7907653 | 0.76 | SLC6A4 (0.75) | SLC6A4SLC6A2CNR1KDM4EMEN1 | |
| SCHEMBL5313499 | 0.74 | SLC6A4 (0.49) | SLC6A4PPARAPPARGSLC6A2 | |
| SCHEMBL20917060 | 0.73 | SLC6A4 (0.61) | SLC6A4CACNA2D1SLC6A2CNR1KDM4E | |
| SCHEMBL20917050 | 0.72 | SLC6A4 (0.57) | SLC6A4CACNA2D1SLC6A2CNR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070208134-A1 | Anti-scarring drug combinations and use thereof | HUNTER WILLIAM L | 2007-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070208134-A1 | Anti-scarring drug combinations and use thereof | MMP1, COL2A1, COL1A1 | SLC6A4 2071/4885PPARA 411/4885PPARG 529/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.