Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 11/20 | 0.56 |
| ▸ | KCNN3 | Q9UGI6 | 6/20 | 0.47 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.46 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.46 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.46 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5454018 | 0.81 | CDK2 (0.67) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL14427341 | 0.79 | CDK2 (0.76) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL5455497 | 0.77 | CDK2 (0.64) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL5452864 | 0.77 | CDK2 (0.67) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL5452857 | 0.74 | CDK2 (0.65) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL13117302 | 0.73 | KCNN3 (0.80) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL29645010 | 0.73 | CDK2 (0.70) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL12953673 | 0.73 | CDK2 (0.70) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL14427337 | 0.72 | CDK2 (1.00) | CDK2KCNN3CCNE1KCNN1KCNN2 | |
| SCHEMBL5451908 | 0.72 | CDK2 (0.72) | CDK2KCNN3CCNE1KCNN1KCNN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | claimed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | claimed |
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-03-15 | — | — | US | disclosed |
| EP-1671962-A1 | NOVEL FUSED HETEROCYCLIC COMPOUND AND USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-06-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070060595-A1 | Novel fused heterocyclic compound and use thereof | JUN, CHUK, RELA | CDK2 284/4885KCNN3 3885/4885CCNE1 223/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.