Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 11/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | IDH1 | O75874 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 3/20 | 0.52 |
| ▸ | APAF1 | O14727 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CASP1 | P29466 | 1/20 | 0.52 |
| ▸ | CASP7 | P55210 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5445669 | 0.90 | KDM4E (0.65) | KDM4EHSD17B10MAPTALOX15ALDH1A1 | |
| SCHEMBL7073150 | 0.77 | KDM4E (0.63) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL4659631 | 0.76 | KDM4E (0.61) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL7075514 | 0.75 | HSD17B10 (0.68) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL4078718 | 0.74 | MAPT (0.69) | KDM4EHSD17B10MAPTALOX15ALDH1A1 | |
| SCHEMBL3846232 | 0.74 | KDM4E (0.56) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL7073003 | 0.73 | HSD17B10 (0.66) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL24277189 | 0.72 | KMT2A (0.58) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL21637918 | 0.72 | ALDH1A1 (0.66) | KDM4EHSD17B10MAPTALOX15TP53 | |
| SCHEMBL2226834 | 0.72 | APLNR (0.63) | TP53ALDH1A1TSHRSMN1; SMN2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | AGRIUS GROUP, LLC. | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287706-A1 | Certain substituted quinolones, compositions, and uses thereof | ABCG2, ATP5ME, ATP5MG | KDM4E 2403/4885HSD17B10 1580/4885MAPT 4297/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.