Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.62 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.62 |
| ▸ | RET | P07949 | 1/20 | 0.52 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.51 |
| ▸ | FLT3 | P36888 | 2/20 | 0.48 |
| ▸ | BRAF | P15056 | 1/20 | 0.48 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.48 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.46 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | MTOR | P42345 | 1/20 | 0.45 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.45 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.45 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459850 | 0.86 | RAB9A (0.64) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5460908 | 0.85 | RAB9A (0.55) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5464860 | 0.83 | MAPKAPK2 (0.48) | RAB9ANPC1SMN1; SMN2POLBP2RY1 | |
| SCHEMBL5467445 | 0.83 | MEN1 (0.56) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5462600 | 0.80 | PIK3CA (0.49) | RAB9ANPC1ALDH1A1SMN1; SMN2MEN1 | |
| SCHEMBL14014120 | 0.80 | RAB9A (0.80) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL22103784 | 0.78 | RAB9A (0.76) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL10078887 | 0.77 | MEN1 (1.00) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL5465585 | 0.77 | RAB9A (0.52) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 | |
| SCHEMBL20788543 | 0.77 | NPC1 (0.77) | RAB9ANPC1ALDH1A1MAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
| EP-1764360-A1 | UREA DERIVATIVE | Sankyo Company, Limited (JP) | 2007-03-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RAB9A 1528/4885NPC1 1089/4885ALDH1A1 731/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.