SCHEMBL5460484

SCHEMBL5460484

CCCCCc1cccc(C=Cc2ccccc2)c1O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.50
PTGS2 P35354 1/20 0.50
TRPA1 O75762 1/20 0.45
BID P55957 3/20 0.44
MCL1 Q07820 3/20 0.44
BCL2L1 Q07817 2/20 0.44
BAK1 Q16611 2/20 0.44
KAT8 Q9H7Z6 2/20 0.44
SAE1 Q9UBE0 2/20 0.44
PPARG P37231 1/20 0.44
PPARA Q07869 1/20 0.44
EP300 Q09472 1/20 0.44
KAT2A Q92830 1/20 0.44
KAT2B Q92831 1/20 0.44
KAT5 Q92993 1/20 0.44
LIPG Q9Y5X9 1/20 0.44
F7 P08709 3/20 0.42
F3 P13726 3/20 0.42
MMP2 P08253 2/20 0.42
KDM4E B2RXH2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7052951 0.86 CHAT (0.46) TRPA1BIDMCL1BCL2L1BAK1
SCHEMBL11352153 0.84 LIPG (0.49) TRPA1BIDMCL1BCL2L1BAK1
SCHEMBL28845923 0.84 LIPG (0.49) TRPA1BIDMCL1BCL2L1BAK1
SCHEMBL30018391 0.83 GABRA1 (0.53) ALOX5PTGS2TRPA1CHATIAPP
SCHEMBL8105367 0.82 TYR (0.42) ALOX5PTGS2TRPA1BIDMCL1
SCHEMBL5460489 0.81 NFE2L2 (0.47) ALOX5PTGS2TRPA1BIDMCL1
SCHEMBL560985 0.81 CHAT (0.47) TRPA1LIPGMAPTCHAT
SCHEMBL4326063 0.81 CHAT (0.47) TRPA1LIPGMAPTCHAT
SCHEMBL9393853 0.79 CHAT (0.43) TRPA1LIPGMAPTCHAT
SCHEMBL9393856 0.79 CHAT (0.43) TRPA1LIPGMAPTCHAT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070191540-A1 LOW DIELECTRIC LOSS RESIN, RESIN COMPOSITION, AND THE MANUFACTURING METHOD OF LOW DIELECTRIC LOSS RESIN HITACHI, LTD. (JP) 2007-08-16 US disclosed