Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B3 | P37058 | 3/20 | 0.61 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.58 |
| ▸ | HSPE1 | P61604 | 1/20 | 0.58 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 8/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 1/20 | 0.55 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.55 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.55 |
| ▸ | GRK6 | P43250 | 1/20 | 0.55 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | DUSP26 | Q9BV47 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.51 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.51 |
| ▸ | MMP2 | P08253 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | THRB | P10828 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5462605 | 1.00 | HSD17B3 (0.61) | HSD17B3HSPD1HSPE1PDE4BMEN1 | |
| SCHEMBL17225206 | 0.83 | DUSP26 (0.70) | HSD17B3HSPD1HSPE1MEN1KMT2A | |
| SCHEMBL5461744 | 0.83 | HSPD1 (0.70) | HSD17B3HSPD1HSPE1PDE4BMEN1 | |
| SCHEMBL5461746 | 0.83 | HSPD1 (0.70) | HSD17B3HSPD1HSPE1PDE4BMEN1 | |
| SCHEMBL5455212 | 0.76 | HSPD1 (0.85) | HSD17B3HSPD1HSPE1MEN1KMT2A | |
| SCHEMBL5455211 | 0.76 | HSPD1 (0.85) | HSD17B3HSPD1HSPE1MEN1KMT2A | |
| SCHEMBL13236133 | 0.75 | HSPD1 (0.75) | HSD17B3HSPD1HSPE1PDE4BMEN1 | |
| SCHEMBL12297880 | 0.75 | CFTR (0.70) | HSD17B3HSPD1HSPE1MEN1KMT2A | |
| SCHEMBL18103083 | 0.75 | MEN1 (0.72) | HSD17B3HSPD1HSPE1PDE4BMEN1 | |
| SCHEMBL20005625 | 0.75 | MEN1 (0.72) | HSD17B3HSPD1HSPE1PDE4BMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN. INC. (JP) | 2007-11-29 | — | — | US | disclosed |
| EP-1666469-A1 | PLASMINOGEN ACTIVATOR INHIBITOR-1 INHIBITOR | Institute of Medicinal Molecular Design, Inc. (JP) | 2006-06-07 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070276011-A1 | Plasminogen Activator Inhibitor-1 Inhibitor | SERPINE1, SERPINC1, SERPINB1 | HSD17B3 2698/4885HSPD1 2213/4885HSPE1 1812/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.