SCHEMBL546443

SCHEMBL546443

C1=C(OCCOC2=CCCC2)CCC1

nearest known ligand 0.35

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
KCNH2 Q12809 1/20 0.32
HRH3 Q9Y5N1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15092951 0.93
SCHEMBL491941 0.93
SCHEMBL6826930 0.92 KCNH2 (0.34) KCNH2HRH3
SCHEMBL6826962 0.90 KCNH2 (0.33) KCNH2HRH3
SCHEMBL8990617 0.87
SCHEMBL9500775 0.86
SCHEMBL16544484 0.86
SCHEMBL16544487 0.85 KDM1A (0.30) KCNH2HRH3
SCHEMBL9499471 0.84 LTA4H (0.35) KCNH2HRH3
SCHEMBL429346 0.84

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 244 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250325456-A1 POLYMER COMPOUNDS AND APPLICATION THEREOF SAMYANG CORPORATION (KR) 2025-10-23 US claimed
EP-4626495-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2025-10-08 EP claimed
CN-119662188-A UV adhesive for packaging GOB of LED display screen, and preparation method and application thereof 河源然生新材料有限公司 2025-03-21 CN claimed
EP-4455175-A1 POLYMER COMPOUND AND APPLICATION THEREOF Samyang Corporation (KR) 2024-10-30 EP claimed
US-12071497-B2 High refractive index, high Abbe compositions Johnson & Johnson Surgical Vision, Inc. (US) 2024-08-27 US claimed
US-20240209129-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. 2024-06-27 US claimed
WO-2024116106-A1 OPHTHALMIC LENS MATERIALS AND DEVICES MADE THEREOF Johnson & Johnson Surgical Vision, Inc. (US) 2024-06-06 WO claimed
US-11795252-B2 Compositions with high refractive index and Abbe number Johnson & Johnson Surgical Vision, Inc. (US) 2023-10-24 US claimed
US-20230279169-A1 HIGH REFRACTIVE INDEX, HIGH ABBE COMPOSITIONS Johnson & Johnson Surgical Vision, Inc. 2023-09-07 US claimed
EP-4237882-A1 COMPOSITIONS WITH HIGH REFRACTIVE INDEX AND ABBE NUMBER Johnson & Johnson Surgical Vision, Inc. (US) 2023-09-06 EP claimed
US-20130164546-A1 MOISTURE-HARDENING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS AND AMINOSILANE ADDUCTS SIKA TECHNOLOGY AG (CH) 2013-06-27 US claimed
US-8399102-B2 Moisture-hardening compositions containing silane-functional polymers and aminosilane adducts SIKA TECHNOLOGY AG (CH) 2013-03-19 US claimed
WO-2013023545-A1 OPTICAL TRANSPARENT DUAL CURE ADHESIVES COMPOSITION HENKEL (CHINA) COMPANY LIMITED (CN) 2013-02-21 WO claimed
US-8110305-B2 Rechargeable lithium battery SAMSUNG SDI CO., LTD. (KR) 2012-02-07 US claimed
US-20100159254-A1 Moisture-Hardening Compositions Containing Silane-Functional Polymers and Aminosilane Adducts SIKA TECHNOLOGY AG (CH) 2010-06-24 US claimed
EP-2013305-B1 MOISTURE-HARDENING COMPOSITIONS CONTAINING SILANE-FUNCTIONAL POLYMERS AND AMINOSILANE ADDUCTS SIKA TECHNOLOGY AG (CH) 2009-10-14 EP claimed
EP-0870749-B1 Reactive coalescents ROHM & HAAS (US) 2003-06-25 EP claimed
US-20020197407-A1 Reactive coalescents SPEECE DAVID GERALD (US) 2002-12-26 US claimed
EP-0870749-A2 Reactive coalescents ROHM AND HAAS COMPANY (US) 1998-10-14 EP claimed
US-4916255-A Method for production of methacrylate ester HITACHI, LTD. (JP) 1990-04-10 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020197407-A1 Reactive coalescents XRCC6, RAD51, CLTA KCNH2 3695/4885HRH3 2794/4885
US-20250325456-A1 POLYMER COMPOUNDS AND APPLICATION THEREOF ILK, PNN, EPCAM KCNH2 3990/4885HRH3 3914/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.