Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.57 |
| ▸ | NPC1 | O15118 | 6/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.57 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.45 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GFER | P55789 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.43 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | FASN | P49327 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5459980 | 0.88 | GFER (0.62) | RAB9ANPC1SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL5460565 | 0.85 | MAPT (0.49) | RAB9ANPC1SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL5456879 | 0.85 | RAB9A (0.59) | RAB9ANPC1SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL5473493 | 0.82 | CYP1A2 (0.46) | RAB9ANPC1SMN1; SMN2CYP1A2CYP2C9 | |
| SCHEMBL5470995 | 0.82 | RAB9A (0.51) | RAB9ANPC1SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL5452210 | 0.80 | RAB9A (0.55) | RAB9ANPC1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5465534 | 0.79 | NPC1 (0.53) | RAB9ANPC1SMN1; SMN2KDM4ECYP1A2 | |
| SCHEMBL5459164 | 0.79 | RAB9A (0.48) | RAB9ANPC1SMN1; SMN2KDM4ETP53 | |
| SCHEMBL5462265 | 0.77 | MAPT (0.48) | RAB9ANPC1SMN1; SMN2TRPV1KDM4E | |
| SCHEMBL5458373 | 0.77 | RBP4 (0.48) | RAB9ASMN1; SMN2HTTTP53MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | SANKYO COMPANY, LIMITED (JP) | 2007-10-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070249620-A1 | Urea Derivative | UGP2, SLC14A1, DGAT1 | RAB9A 1528/4885NPC1 1089/4885SMN1; SMN2 4424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.