Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5395468 | 0.90 | LMNA (0.45) | POLBLMNAGAAHPGDALDH1A1 | |
| SCHEMBL5466341 | 0.81 | LMNA (0.39) | POLBLMNAGAAHPGDALDH1A1 | |
| SCHEMBL5343117 | 0.77 | ALDH1A1 (0.41) | POLBGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL5403419 | 0.71 | GAA (0.42) | POLBGAAHPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL4905703 | 0.71 | LMNA (0.62) | POLBLMNAHPGDALDH1A1HSD17B10 | |
| SCHEMBL5375181 | 0.71 | MAPT (0.46) | POLBLMNAGAAHPGDALDH1A1 | |
| SCHEMBL5377050 | 0.71 | SMN1; SMN2 (0.41) | POLBLMNAGAAHPGDALDH1A1 | |
| SCHEMBL4903975 | 0.71 | LMNA (0.50) | LMNAHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL4899425 | 0.69 | LMNA (0.58) | LMNAHPGDALDH1A1HSD17B10MCL1 | |
| SCHEMBL11819253 | 0.69 | KMT2A (0.67) | LMNAGAAALDH1A1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007091140-A1 | SUBSTITUTED PHENYLSULFAMOYL COMPOUNDS AS PPAR AGONISTS | PFIZER PRODUCTS INC. (US) | 2007-08-16 | — | — | WO | disclosed |