Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | UGCG | Q16739 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9181002 | 0.96 | ALDH1A1 (0.46) | ALDH1A1HTTXBP1TSHRBLM | |
| SCHEMBL3348647 | 0.92 | CYP1A2 (0.47) | ALDH1A1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL30618514 | 0.92 | CYP1A2 (0.47) | ALDH1A1CYP1A2CYP11B1CYP11B2 | |
| SCHEMBL467497 | 0.83 | ALDH1A1 (0.47) | ALDH1A1CYP1A2HPGDKDM4E | |
| SCHEMBL4819783 | 0.83 | HSD17B1 (0.56) | KMT2ACYP11B1CYP11B2TP53MEN1 | |
| SCHEMBL4632528 | 0.83 | HSD17B1 (0.56) | KMT2ACYP11B1CYP11B2TP53MEN1 | |
| SCHEMBL2358440 | 0.83 | HSD17B1 (0.56) | KMT2ACYP11B1CYP11B2TP53MEN1 | |
| SCHEMBL19984866 | 0.82 | CYP1A2 (0.49) | TSHRCYP1A2 | |
| SCHEMBL10529556 | 0.82 | CYP11B1 (0.43) | ALDH1A1HTTXBP1CYP11B1CYP11B2 | |
| SCHEMBL3854355 | 0.82 | FFAR1 (0.45) | ALDH1A1CYP11B1CYP11B2HPGDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3512843-B1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-20 | — | — | EP | disclosed |
| US-11136292-B2 | Plant growth regulator compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2021-10-05 | — | — | US | disclosed |
| CN-109320496-B | Selenocyanization reagent and preparation method and application thereof | 南宁师范大学 | 2020-10-16 | — | — | CN | disclosed |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-10-31 | — | — | US | disclosed |
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | BAYER HEALTHCARE AG (DE) | 2007-05-24 | — | — | US | disclosed |
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | BAYER HEALTHCARE AG (DE) | 2007-05-24 | — | — | US | disclosed |
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | BAYER HEALTHCARE AG (DE) | 2007-05-24 | — | — | US | disclosed |
| EP-1654227-A1 | BICYCLIC INDOLINE SULFONAMIDE DERIVATIVES | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016881-A1 | BICYCLIC INDOLINE SULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2005-02-24 | — | — | WO | disclosed |
| US-6133446-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 2000-10-17 | — | — | US | disclosed |
| US-5877317-A | Heterocyclic compounds for the treatment of CNS and cardiovascular disorders | PHARMACIA & UPJOHN COMPANY (US) | 1999-03-02 | — | — | US | disclosed |
| EP-0737189-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | PHARMACIA & UPJOHN COMPANY (US) | 1996-10-16 | — | — | EP | disclosed |
| EP-0490772-B1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR (FR) | 1995-07-26 | — | — | EP | disclosed |
| WO-1995018118-A1 | HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF CNS AND CARDIOVASCULAR DISORDERS | THE UPJOHN COMPANY (US) | 1995-07-06 | — | — | WO | disclosed |
| US-5194437-A | Substituted with oxygen containing heterocycle, central nervous system disorders, neuroendocrine disorders | ADIR ET COMPAGNIE (FR) | 1993-03-16 | — | — | US | disclosed |
| EP-0490772-A1 | 1,4-Disubstituted piperazines, their process of preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1992-06-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | PPARD, PPARA, PPARG | ALDH1A1 2025/4885HTT 3635/4885XBP1 1784/4885 |
| US-11136292-B2 | Plant growth regulator compounds | FGF1, MST1, CDC20 | ALDH1A1 3543/4885HTT 4509/4885XBP1 1470/4885 |
| US-20190330148-A1 | PLANT GROWTH REGULATOR COMPOUNDS | FGF1, MST1, CDC20 | ALDH1A1 3543/4885HTT 4509/4885XBP1 1470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.