Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | F10 | P00742 | 11/20 | 0.43 |
| ▸ | F2 | P00734 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475392 | 0.90 | TP53 (0.46) | LMNATP53F10F2ENPP2 | |
| SCHEMBL5482637 | 0.90 | LMNA (0.48) | LMNATP53F10F2ENPP2 | |
| SCHEMBL5469270 | 0.90 | LMNA (0.45) | LMNATP53F10F2ENPP2 | |
| SCHEMBL5472452 | 0.87 | TP53 (0.44) | LMNATP53F10F2ENPP2 | |
| SCHEMBL5472430 | 0.86 | F10 (0.47) | LMNATP53F10F2ENPP2 | |
| SCHEMBL5472036 | 0.85 | TP53 (0.46) | LMNATP53F10F2ENPP2 | |
| SCHEMBL14582533 | 0.84 | HTR6 (0.51) | LMNATP53F10F2 | |
| SCHEMBL5469092 | 0.84 | TP53 (0.45) | LMNATP53F10F2 | |
| SCHEMBL5472479 | 0.79 | TP53 (0.47) | LMNATP53F10ENPP2 | |
| SCHEMBL5469178 | 0.77 | TP53 (0.45) | LMNATP53ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070032473-A1 | Substituted amides and their use as medicaments | GERLACH KAI | 2007-02-08 | — | — | US | disclosed |
| US-20070032473-A1 | Substituted amides and their use as medicaments | GERLACH KAI | 2007-02-08 | — | — | US | disclosed |
| US-20070032473-A1 | Substituted amides and their use as medicaments | GERLACH KAI | 2007-02-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070032473-A1 | Substituted amides and their use as medicaments | OAT, HLA-B, BCAT2 | LMNA 1681/4885TP53 2817/4885F10 1757/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.