Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856035 | 0.88 | LMNA (0.41) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5815622 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5479186 | 0.82 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2IDO1 | |
| SCHEMBL855865 | 0.80 | ALDH1A1 (0.39) | ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5812511 | 0.80 | LMNA (0.36) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL5822313 | 0.79 | SMN1; SMN2 (0.50) | ALDH1A1LMNASMN1; SMN2IDO1KDM4E | |
| SCHEMBL5814625 | 0.79 | MAP4K4 (0.40) | ALDH1A1LMNASMN1; SMN2KDM4EMAPT | |
| SCHEMBL5814649 | 0.76 | CA12 (0.36) | IDO1NTRK1 | |
| SCHEMBL5815110 | 0.76 | ALDH1A1 (0.51) | ALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL31749981 | 0.73 | GPR52 (0.33) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | ITO MASHITO | 2007-07-19 | — | — | US | disclosed |
| WO-2006136327-A1 | FUNGICIDAL BENZYLPYRIMIDINE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2006-12-28 | — | — | WO | disclosed |
| EP-1718305-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | Bayer CropScience AG (DE) | 2006-11-08 | — | — | EP | disclosed |
| WO-2005079798-A1 | PYRIMIDINE DERIVATIVES AND USE THEREOF AS AGRICULTURAL AND HORTICULTURAL FUNGICIDES | BAYER CROPSCIENCE AG (DE) | 2005-09-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070167421-A1 | Pyrimidine derivatives and use thereof as agricultural and horticultural fungicides | DPYD, DHFR, TYMP | ALDH1A1 697/4885LMNA 4712/4885SMN1; SMN2 3837/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.