Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | KDM6A | O15550 | 1/20 | 0.33 |
| ▸ | KDM4A | O75164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM5C | P41229 | 1/20 | 0.33 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.33 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.33 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.33 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4622919 | 0.85 | LMNA (0.40) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL10566488 | 0.84 | — | — | |
| SCHEMBL15906247 | 0.79 | TYR (0.37) | ADORA2BPDE4APDE4BPDE4CPDE4D | |
| SCHEMBL14257134 | 0.76 | — | — | |
| SCHEMBL18686731 | 0.76 | ALDH1A1 (0.42) | PDE4APDE4BPDE4CPDE4DALDH1A1 | |
| SCHEMBL4842898 | 0.74 | — | — | |
| SCHEMBL30526236 | 0.74 | LMNA (0.38) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL14652120 | 0.74 | HTT (0.39) | HSD17B10ALDH1A1 | |
| SCHEMBL27298478 | 0.74 | ALDH1A1 (0.42) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL3590708 | 0.74 | ALDH1A1 (0.43) | LMNAADORA2BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118354759-A | Compositions comprising 2' -deoxycytidine analogs and their use for treating sickle cell disease, thalassemia and cancer | 阿基拉比奥有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116209439-A | Substituted N- (2, 6-dioxopiperidin-3-yl) -1, 3-dioxoisoindolin-5-yl) arylsulfonamide analogs as cereblon modulators | 圣裘德儿童研究医院有限公司 | 2023-06-02 | — | — | CN | disclosed |
| US-20070190143-A1 | Disintegrating tablets comprising licarb azepine | NOVARTIS AG (CH) | 2007-08-16 | — | — | US | disclosed |
| EP-1729737-A1 | DISINTEGRATING TABLETS COMPRISING LICARBAZEPINE | Novartis AG (CH) | 2006-12-13 | — | — | EP | disclosed |
| WO-2005092290-A1 | DISINTEGRATING TABLETS COMPRISING LICARBAZEPINE | NOVARTIS AG (CH) | 2005-10-06 | — | — | WO | disclosed |
| CN-1037346-C | Therapeutic agents | BOOTS CO LTD (GB) | 1998-02-11 | — | — | CN | disclosed |