Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | HEXA | P06865 | 1/20 | 0.32 |
| ▸ | HEXB | P07686 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469536 | 0.85 | LMNA (0.40) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL5707715 | 0.77 | TP53 (0.30) | — | |
| SCHEMBL13499301 | 0.73 | DRD2 (0.36) | LMNAADORA2BKMT2A | |
| SCHEMBL11046099 | 0.72 | ALDH1A1 (0.38) | LMNACA1CA2 | |
| SCHEMBL1724271 | 0.69 | PSMB1 (0.50) | LMNA | |
| SCHEMBL4052355 | 0.69 | — | — | |
| SCHEMBL4448355 | 0.69 | — | — | |
| SCHEMBL35878 | 0.67 | PDE4A (0.39) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL12094978 | 0.67 | ASH1L (0.35) | LMNACA1CA2KDM4ECA12 | |
| SCHEMBL9387299 | 0.65 | LPO (0.52) | LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1601335-B1 | MEANS AND METHOD FOR THE SIMULTANEOUS BLEACHING AND DYEING OF KERATIN FIBRES | WELLA AG (DE) | 2008-03-19 | — | — | EP | claimed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | claimed |
| US-7429274-B2 | Agent and method for the oxidative coloring of keratin fibers | WELLA AG (DE) | 2008-09-30 | — | — | US | disclosed |
| CN-101132760-A | Agent and method for colouring keratin fibres | PROCTER & GAMBLE (US) | 2008-02-27 | — | — | CN | disclosed |
| US-7326254-B2 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | WELLA AG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-7244278-B2 | Agent and method for oxidative coloring of keratin fibers | WELLA AG (DE) | 2007-07-17 | — | — | US | disclosed |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | Wella GmbH (DE) | 2007-04-12 | — | — | US | disclosed |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2007-03-29 | — | — | US | disclosed |
| EP-1754514-A1 | Agent and method for colouring keratin fibres | Wella Aktiengesellschaft (DE) | 2007-02-21 | — | — | EP | disclosed |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | PROCTER & GAMBLE COMPANY, THE | 2007-01-04 | — | — | US | disclosed |
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | HFC PRESTIGE INTERNATIONAL HOLDING SWITZERLAND S.A.R.L (CH) | 2006-07-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060162096-A1 | Means and method for the simultaneous bleaching and dyeing of keratin fibres | KRT18, GPX4, NOX4 | LMNA 984/4885ADORA2B 4249/4885PDE4A 2585/4885 |
| US-20070067927-A1 | Agent and method for oxidative coloring of keratin fibers | KRT18, KIT, AOC1 | LMNA 90/4885ADORA2B 3389/4885PDE4A 4146/4885 |
| US-20070000073-A1 | Agent and method for colouring keratin fibres | KRT18, CDC73, OAT | LMNA 809/4885ADORA2B 4872/4885PDE4A 4012/4885 |
| US-20070079452-A1 | Agent and method for the oxidative coloring of keratin fibers | KRT18, KIT, CKMT1A; CKMT1B | LMNA 103/4885ADORA2B 4580/4885PDE4A 3673/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.