Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5469536 | 0.74 | LMNA (0.40) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL4622919 | 0.67 | LMNA (0.40) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL10566488 | 0.62 | — | — | |
| SCHEMBL2730449 | 0.61 | PDE4A (0.41) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL2614957 | 0.61 | HTT (0.42) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL25980045 | 0.60 | LMNA (0.46) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL25980044 | 0.59 | ADORA2B (0.45) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL35878 | 0.58 | PDE4A (0.39) | LMNAADORA2BPDE4APDE4BPDE4C | |
| SCHEMBL11929541 | 0.57 | ALDH1A1 (0.59) | LMNAADORA2BHSD17B10 | |
| SCHEMBL9387299 | 0.57 | LPO (0.52) | LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116209439-B | Cereblon protein modulators | Saint Jude Children's Research Hospital Ltd. (US) | 2026-05-26 | — | — | CN | disclosed |
| CN-119894510-A | Hydroxylamine-based EGFR inhibitors for the treatment of brain metastasis | 乔治亚大学研究基金会 | 2025-04-25 | — | — | CN | disclosed |
| CN-118354759-A | Compositions comprising 2' -deoxycytidine analogs and their use for treating sickle cell disease, thalassemia and cancer | 阿基拉比奥有限公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-116209439-A | Substituted N- (2, 6-dioxopiperidin-3-yl) -1, 3-dioxoisoindolin-5-yl) arylsulfonamide analogs as cereblon modulators | 圣裘德儿童研究医院有限公司 | 2023-06-02 | — | — | CN | disclosed |