Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.69 |
| ▸ | MAPT | P10636 | 5/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.69 |
| ▸ | HTT | P42858 | 4/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.69 |
| ▸ | POLB | P06746 | 3/20 | 0.69 |
| ▸ | KPNA2 | P52292 | 1/20 | 0.69 |
| ▸ | LMNA | P02545 | 4/20 | 0.68 |
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.52 |
| ▸ | DUSP10 | Q9Y6W6 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5468199 | 0.82 | KDM4E (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5462701 | 0.81 | KDM4E (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5472904 | 0.74 | CYP1A2 (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL11296578 | 0.72 | LMNA (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL12330249 | 0.70 | CYP1A2 (0.62) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL29929637 | 0.70 | CYP1A2 (0.66) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4986074 | 0.70 | CYP1A2 (0.66) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5469070 | 0.70 | KDM4E (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL5462657 | 0.70 | KDM4E (1.00) | KDM4EMAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL13373267 | 0.69 | CYP1A2 (0.58) | KDM4EMAPTALDH1A1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | KDM4E 2371/4885MAPT 4503/4885ALDH1A1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.