Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.39 |
| ▸ | CCR5 | P51681 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL208454 | 0.88 | ALDH1A1 (0.53) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL207910 | 0.86 | OPRM1 (0.50) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL205735 | 0.86 | ALDH1A1 (0.55) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL205753 | 0.85 | SIGMAR1 (0.45) | SIGMAR1EPHX2HPGDTHRBOPRM1 | |
| SCHEMBL207808 | 0.84 | HPGD (0.55) | SIGMAR1ALDH1A1KMT2AHPGDTHRB | |
| SCHEMBL206988 | 0.83 | ALDH1A1 (0.51) | ALDH1A1KMT2AEPHX2HPGDTHRB | |
| SCHEMBL206071 | 0.83 | CNR1 (0.52) | SIGMAR1KMT2AHPGDCYP3A4CYP2C19 | |
| SCHEMBL207130 | 0.83 | SMN1; SMN2 (0.42) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL206650 | 0.83 | KMT2A (0.44) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD | |
| SCHEMBL208794 | 0.83 | ALDH1A1 (0.44) | SIGMAR1ALDH1A1KMT2AEPHX2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | GRUENENTHAL GMBH (DE) | 2007-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070112007-A1 | Cyclohexyl-1, 4-diamine compounds | PKD1, DDC, DPYD | SIGMAR1 3262/4885ALDH1A1 158/4885KMT2A 3604/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.