Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 4/20 | 0.55 |
| ▸ | CCNA2 | P20248 | 4/20 | 0.55 |
| ▸ | CDK2 | P24941 | 4/20 | 0.55 |
| ▸ | CDK9 | P50750 | 4/20 | 0.55 |
| ▸ | CDK5 | Q00535 | 4/20 | 0.55 |
| ▸ | CDK5R1 | Q15078 | 4/20 | 0.55 |
| ▸ | CCNA1 | P78396 | 3/20 | 0.55 |
| ▸ | GSK3B | P49841 | 2/20 | 0.44 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.44 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.44 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.41 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR7 | P34969 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5465203 | 0.83 | ROCK1 (0.49) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL30507533 | 0.81 | CDK5 (0.59) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL28501601 | 0.81 | CDK5 (0.59) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL5471286 | 0.78 | GSK3B (0.60) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL5469279 | 0.72 | RAB9A (0.60) | POLB | |
| SCHEMBL5465912 | 0.72 | NPSR1 (0.49) | CCNT1CDK9CDK5GSK3B | |
| SCHEMBL6640492 | 0.71 | CCNT1 (0.58) | CCNT1CCNA2CDK2CDK9CDK5 | |
| SCHEMBL5467291 | 0.71 | CCNT1 (0.44) | CCNT1CCNA2CDK2CDK9GSK3B | |
| SCHEMBL5476961 | 0.71 | CDK1 (0.49) | CCNT1CCNA2CDK2CDK9CDK5 | |
| Meriolin 6 SCHEMBL2999009 | 0.71 | CDK5 (1.00) | CCNT1CCNA2CDK2CDK9CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | CCNT1 1660/4885CCNA2 1893/4885CDK2 3499/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.