Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467426 | 0.91 | F2 (0.39) | MEN1KMT2AALDH1A1HPGDAKT1 | |
| SCHEMBL5472490 | 0.81 | ALDH1A1 (0.52) | MEN1KMT2AALDH1A1HPGDAKT1 | |
| SCHEMBL5465185 | 0.77 | ALDH1A1 (0.41) | ALDH1A1HPGDPOLBSMN1; SMN2HTT | |
| SCHEMBL5460284 | 0.74 | ALDH1A1 (0.45) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5472425 | 0.73 | MAPT (0.44) | ALDH1A1PTGS2NPSR1CYP1A2CYP2C9 | |
| SCHEMBL5471322 | 0.73 | L3MBTL1 (0.46) | MEN1KMT2AALDH1A1HPGDAKT1 | |
| SCHEMBL5476994 | 0.73 | CYP17A1 (0.47) | MEN1KMT2AALDH1A1HPGDPOLB | |
| SCHEMBL5462677 | 0.72 | AKT1 (0.39) | MEN1KMT2AALDH1A1AKT1PIK3CA | |
| SCHEMBL5470760 | 0.71 | KDM4E (0.42) | MEN1KMT2AALDH1A1POLBSMN1; SMN2 | |
| SCHEMBL5467291 | 0.71 | CCNT1 (0.44) | MEN1KMT2AALDH1A1L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | claimed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | claimed |
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | MEN1 2400/4885KMT2A 2631/4885ALDH1A1 2447/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.