Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | PDE4A | P27815 | 2/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3816675 | 0.90 | LMNA (0.55) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3983514 | 0.88 | ALDH1A1 (0.51) | LMNAALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL3983498 | 0.88 | ALDH1A1 (0.51) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3983501 | 0.87 | LMNA (0.42) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3811662 | 0.85 | LMNA (0.52) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL4396358 | 0.83 | ALDH1A1 (0.48) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL5469836 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| Formic Acid SCHEMBL4392627 | 0.83 | LMNA (0.49) | LMNASMN1; SMN2ALDH1A1HPGDKDM4E | |
| SCHEMBL3815910 | 0.81 | LMNA (0.49) | LMNAALDH1A1HPGDKDM4ETSHR | |
| SCHEMBL27634843 | 0.80 | IDO1 (0.35) | LMNAALDH1A1HPGDKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070213283-A1 | Macrolides substituted at the 4\"-position | GLAXO GROUP LIMITED (GB) | 2007-09-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213283-A1 | Macrolides substituted at the 4\"-position | IL4, CYP51A1, IL17A | LMNA 2144/4885SMN1; SMN2 1956/4885ALDH1A1 2288/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.