Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | LDHA | P00338 | 3/20 | 0.41 |
| ▸ | LDHB | P07195 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.37 |
| ▸ | GABRD | O14764 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918082 | 0.87 | KDM4E (0.44) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| SCHEMBL8106142 | 0.84 | CYP3A4 (0.54) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| SCHEMBL7016016 | 0.83 | KMT2A (0.41) | CYP3A4KMT2AKDM4ETDP1MEN1 | |
| SCHEMBL27451659 | 0.83 | CYP3A4 (0.45) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| SCHEMBL844533 | 0.82 | CYP3A4 (0.49) | CYP3A4KMT2ATDP1MEN1MAPK1 | |
| SCHEMBL29918124 | 0.82 | ALDH1A1 (0.44) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL5042476 | 0.81 | CYP3A4 (0.52) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| Hydrochloric Acid SCHEMBL5037307 | 0.81 | CYP3A4 (0.52) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| SCHEMBL11204746 | 0.81 | ALDH1A1 (0.45) | CYP3A4ACHEKMT2AKDM4ETDP1 | |
| SCHEMBL15957633 | 0.81 | KDM4E (0.47) | CYP3A4ACHEKMT2AKDM4ETDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8552015-B2 | Quinazolinone derivatives and their use as CB agonists | NOVARTIS AG (CH) | 2013-10-08 | — | — | US | disclosed |
| US-20070265285-A1 | Quinazolinone derivatives and their use as CB agonists | NOVARTIS AG (CH) | 2007-11-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070265285-A1 | Quinazolinone derivatives and their use as CB agonists | CNR1, ADRB1, ADRA1D | CYP3A4 91/4885ACHE 838/4885KMT2A 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.