Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | GFER | P55789 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.38 |
| ▸ | IMPDH2 | P12268 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | G6PD | P11413 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10921308 | 0.84 | CISD2 (0.45) | KMT2AMEN1POLBMAPTCYP3A4 | |
| SCHEMBL5472015 | 0.83 | CYP3A4 (0.45) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL28887578 | 0.80 | HSD17B10 (0.43) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL12552999 | 0.80 | CYP3A4 (0.52) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL29918082 | 0.79 | KDM4E (0.44) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL28812075 | 0.76 | CA12 (0.46) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL3008135 | 0.74 | IMPDH2 (0.41) | POLBGFERCYP3A4ALDH1A1IMPDH2 | |
| SCHEMBL29918124 | 0.74 | ALDH1A1 (0.44) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL14511729 | 0.73 | CYP3A4 (0.56) | KMT2AMEN1POLBTDP1MAPT | |
| SCHEMBL18786818 | 0.73 | TPMT (0.54) | KMT2AMEN1POLBTDP1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003106435-A1 | FUSED-RING PYRIMIDIN-4(3H)-ONE DERIVATIVES, PROCESSES FOR THE PREPARATION AND USES THEREOF | SANKYO COMPANY, LIMITED (JP) | 2003-12-24 | — | — | WO | disclosed |