Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 2/20 | 0.38 |
| ▸ | TTR | P02766 | 1/20 | 0.38 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD5 | P21918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7118433 | 0.98 | ESR2 (0.45) | ESR2CYP3A4CA2CA5AESR1 | |
| SCHEMBL30196584 | 0.84 | CYP3A4 (0.41) | ESR2CYP3A4CA2CA5AESR1 | |
| SCHEMBL7619670 | 0.84 | CYP3A4 (0.41) | ESR2CYP3A4CA2CA5AESR1 | |
| Hydrochloric Acid SCHEMBL6042032 | 0.82 | CYP3A4 (0.39) | ESR2CYP3A4CA2CA5AESR1 | |
| SCHEMBL276962 | 0.78 | — | — | |
| SCHEMBL6917418 | 0.76 | CYP1A2 (0.31) | ALDH1A1MAPTHSD17B10 | |
| SCHEMBL5537608 | 0.76 | — | — | |
| SCHEMBL10426767 | 0.76 | MAPT (0.40) | CA2KDM4EALDH1A1MAPTMAPK1 | |
| SCHEMBL2011445 | 0.76 | — | — | |
| SCHEMBL5644783 | 0.76 | CA1 (0.31) | CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 58 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117393035-A | Method for analyzing medicinal components of astragalus glue whitening capsules for treating leukopenia by network pharmacology mode and application thereof | 贵州汉方药业有限公司 | 2024-01-12 | — | — | CN | claimed |
| US-9078891-B2 | 7-hydroxy chromones as potent antioxidants | UNIGEN, INC. (US) | 2015-07-14 | — | — | US | claimed |
| US-20130012458-A1 | 7-HYDROXY CHROMONES AS POTENT ANTIOXIDANTS | UNIGEN, INC. (US) | 2013-01-10 | — | — | US | claimed |
| EP-1503777-B1 | 7-Hydroxy chromones as potent antioxidants | UNIGEN INC (US) | 2012-08-22 | — | — | EP | claimed |
| US-20100168223-A1 | 7-Hydroxy Chromones As Potent Antioxidants | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-07-01 | — | — | US | claimed |
| US-7678772-B2 | 7-hydroxy chromones as potent antioxidants | UNIGEN PHARMACEUTICALS, INC. (US) | 2010-03-16 | — | — | US | claimed |
| EP-1503777-A4 | 7-HYDROXY CHROMONES AS POTENT ANTIOXIDANTS | UNIGEN PHARMACEUTICALS INC (US) | 2008-02-20 | — | — | EP | claimed |
| US-20050164957-A1 | 7-Hydroxy chromones as potent antioxidants | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-07-28 | — | — | US | claimed |
| US-6884783-B2 | 7-Hydroxy chromones as potent antioxidants | UNIGEN PHARMACEUTICALS, INC. (US) | 2005-04-26 | — | — | US | claimed |
| EP-1503777-A1 | 7-HYDROXY CHROMONES AS POTENT ANTIOXIDANTS | Unigen Pharmaceuticals, Inc. (US) | 2005-02-09 | — | — | EP | claimed |
| WO-2003092713-A1 | 7-HYDROXY CHROMONES AS POTENT ANTIOXIDANTS | UNIGEN PHARMACEUTICALS, INC. (US) | 2003-11-13 | — | — | WO | claimed |
| US-20030207818-A1 | Identification and purification of 7-hydroxychromes that exhibit potent antioxidant activity. In one embodiment the present invention includes a method for providing an antioxidant to a host in need thereof, comprising | UNIGEN, INC. | 2003-11-06 | — | — | US | claimed |
| JP-10245391-A | — | — | None | — | — | JP | disclosed |
| CN-120289476-A | Synthesis method of drug intermediate | 安徽大学 | 2025-07-11 | — | — | CN | disclosed |
| CN-114302879-A | Selective estrogen receptor degraders | 太阳医药高级研究有限公司 | 2022-04-08 | — | — | CN | disclosed |
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | OLEMA PHARMACEUTICALS, INC. (US) | 2015-07-16 | — | — | US | disclosed |
| US-4267377-A | Intermediates for steroid synthesis | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
| US-3994926-A | Aryl ketals of polycyclic oxo compounds and processes | HOFFMANN-LA ROCHE INC. (US) | 1976-11-30 | — | — | US | disclosed |
| US-3989724-A | Tetrahydropyran-2-ols | HOFFMANN-LA ROCHE INC. (US) | 1976-11-02 | — | — | US | disclosed |
| US-3950358-A | ARYL KETALS OF 3,7-DIHYDROXY-11-OXO-DODEC-1-ENE | HOFFMANN-LA ROCHE INC. (US) | 1976-04-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150197506-A1 | NOVEL BENZOPYRAN COMPOUNDS, COMPOSITIONS AND USES THEREOF | ESR2, GPER1, ESR1 | ESR2 1/4885CYP3A4 123/4885CA2 3836/4885 |
| US-20100168223-A1 | 7-Hydroxy Chromones As Potent Antioxidants | CYP27A1, NOX4, ROS1 | ESR2 406/4885CYP3A4 94/4885CA2 2013/4885 |
| US-20030207818-A1 | Identification and purification of 7-hydroxychromes that exhibit potent antioxidant activity. In one embodiment the present invention includes a method for providing an antioxidant to a host in need thereof, comprising | NQO1, KEAP1, NOX4 | ESR2 1264/4885CYP3A4 139/4885CA2 1700/4885 |
| US-20050164957-A1 | 7-Hydroxy chromones as potent antioxidants | CYP27A1, NOX4, ROS1 | ESR2 406/4885CYP3A4 94/4885CA2 2013/4885 |
| US-20130012458-A1 | 7-HYDROXY CHROMONES AS POTENT ANTIOXIDANTS | CYP27A1, ROS1, CYP27B1 | ESR2 822/4885CYP3A4 276/4885CA2 3569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.