Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.70 |
| ▸ | RAB9A | P51151 | 9/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.70 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.55 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.55 |
| ▸ | SRC | P12931 | 1/20 | 0.55 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5472912 | 0.89 | RAB9A (0.74) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5467105 | 0.88 | RAB9A (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5465929 | 0.88 | NPC1 (0.70) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5471757 | 0.87 | NPC1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5472432 | 0.87 | RAB9A (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5471285 | 0.85 | ALDH1A1 (0.65) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5472905 | 0.84 | NPC1 (0.64) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5466020 | 0.83 | RAB9A (0.67) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5465340 | 0.82 | ALDH1A1 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA | |
| SCHEMBL5477991 | 0.82 | SMN1; SMN2 (0.61) | NPC1RAB9ASMN1; SMN2ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | ONO PHARMACEUTICAL CO., LTD. (JP) | 2007-05-03 | — | — | US | disclosed |
| EP-1679309-A1 | ANTISTRESS DRUG AND MEDICAL USE THEREOF | ONO PHARMACEUTICAL CO., LTD. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099938-A1 | Antistress drug and medical use thereof | NPSR1, MC2R, SRR | NPC1 1950/4885RAB9A 3039/4885SMN1; SMN2 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.