Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | SCN9A | Q15858 | 18/20 | 0.49 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.44 |
| ▸ | SCN7A | Q01118 | 2/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27902504 | 0.84 | BACE1 (0.58) | BACE1SCN9ASCN10ACNR2SCN7A | |
| SCHEMBL30387658 | 0.84 | BACE1 (0.58) | BACE1SCN9ASCN10ACNR2SCN7A | |
| SCHEMBL1285735 | 0.79 | BACE1 (0.56) | BACE1SCN9ASCN10ACNR2SCN7A | |
| SCHEMBL14597743 | 0.78 | KDM4C (0.60) | SCN9ASCN10A | |
| Hydrochloric Acid SCHEMBL23294630 | 0.76 | ATF4 (0.54) | BACE1SCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL5471599 | 0.76 | SCN9A (0.59) | SCN9ASCN10ASCN7AKCNH2SCN5A | |
| SCHEMBL21384521 | 0.75 | ATF4 (0.55) | BACE1SCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL21390178 | 0.74 | ATF4 (0.54) | BACE1SCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL21390322 | 0.74 | ATF4 (0.48) | SCN9ASCN10ASCN7AKCNH2SCN5A | |
| SCHEMBL23333308 | 0.74 | ATF4 (0.54) | SCN9ASCN10ASCN7AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | PFIZER INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | PFIZER INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | PFIZER INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | CETP, LCAT, MTTP | BACE1 1346/4885SCN9A 4543/4885SCN10A 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.