Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.60 |
| ▸ | SCN9A | Q15858 | 19/20 | 0.55 |
| ▸ | SCN10A | Q9Y5Y9 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31733635 | 0.82 | KDM4C (0.65) | KDM4CSCN9A | |
| SCHEMBL5471599 | 0.81 | SCN9A (0.59) | SCN9ASCN10A | |
| SCHEMBL1285735 | 0.80 | BACE1 (0.56) | SCN9ASCN10A | |
| SCHEMBL5474090 | 0.78 | BACE1 (0.51) | SCN9ASCN10A | |
| SCHEMBL30387658 | 0.76 | BACE1 (0.58) | SCN9ASCN10A | |
| SCHEMBL1220183 | 0.76 | KDM4C (1.00) | KDM4C | |
| SCHEMBL27902504 | 0.76 | BACE1 (0.58) | SCN9ASCN10A | |
| SCHEMBL25199807 | 0.75 | DDR1 (0.51) | — | |
| SCHEMBL21384521 | 0.75 | ATF4 (0.55) | SCN9ASCN10A | |
| SCHEMBL14147908 | 0.75 | SCN9A (0.52) | SCN9ASCN10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | PFIZER INC. | 2007-01-04 | — | — | US | disclosed |
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | PFIZER INC. | 2007-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004774-A1 | Cept inhibitors and metabolites thereof | CETP, LCAT, MTTP | KDM4C 4574/4885SCN9A 4543/4885SCN10A 4663/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.