Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.53 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10270281 | 0.92 | PPARD (0.56) | — | |
| Hydrochloric Acid SCHEMBL9522094 | 0.83 | HTR6 (0.70) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL30299240 | 0.83 | HTR6 (0.70) | HTR6SIGMAR1 | |
| SCHEMBL10175568 | 0.82 | SIGMAR1 (0.57) | HTR6SIGMAR1 | |
| SCHEMBL1430487 | 0.82 | PPARD (0.69) | KDM4C | |
| SCHEMBL2878638 | 0.82 | PPARD (0.69) | KDM4C | |
| SCHEMBL2883493 | 0.82 | PPARD (0.69) | KDM4C | |
| SCHEMBL2207814 | 0.81 | HTR6 (0.71) | HTR6SIGMAR1 | |
| Hydrochloric Acid SCHEMBL9523635 | 0.81 | KDM4C (0.53) | SIGMAR1KDM4C | |
| Hydrochloric Acid SCHEMBL9520181 | 0.81 | HTR6 (0.57) | HTR6SIGMAR1KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | SCHERING AG (DE) | 2007-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070129358-A1 | Sbstituted chroman derivatives, processes for their preparation and their use as antiinflammatory agents | TNF, CXCL8, MPO | HTR6 770/4885SIGMAR1 1559/4885KDM4C 3261/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.