Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 6/20 | 0.61 |
| ▸ | AVPR1A | P37288 | 4/20 | 0.61 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4942676 | 0.91 | OXTR (0.73) | OXTRAVPR1APTPN1HDAC8TAAR1 | |
| SCHEMBL5759282 | 0.91 | OXTR (0.73) | OXTRAVPR1APTPN1HDAC8TAAR1 | |
| SCHEMBL5043513 | 0.85 | AVPR1A (0.62) | OXTRAVPR1AROCK2 | |
| SCHEMBL7083271 | 0.85 | OXTR (0.83) | OXTRAVPR1APRSS1ROCK2ROCK1 | |
| SCHEMBL4945458 | 0.85 | OXTR (0.83) | OXTRAVPR1APRSS1ROCK2ROCK1 | |
| SCHEMBL4942915 | 0.81 | AVPR1A (0.75) | OXTRAVPR1A | |
| SCHEMBL7086467 | 0.81 | AVPR1A (0.75) | OXTRAVPR1A | |
| SCHEMBL7083946 | 0.81 | AVPR1A (0.59) | OXTRAVPR1A | |
| SCHEMBL4939162 | 0.81 | OXTR (0.73) | OXTRAVPR1AHDAC8MEN1KMT2A | |
| SCHEMBL4944329 | 0.81 | OXTR (0.73) | OXTRAVPR1AHDAC8MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211601-B2 | Pharmaceutically active pyrrolidine derivatives | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2007-05-01 | — | — | US | disclosed |